As a sophomore at Rice University in 2010, Anthony received citations as the national Player of the Year from the National Collegiate Baseball Writers Association, American Baseball Coaches Association and Baseball America after hitting .394 with a career-high 26 home runs and 85 RBI. He joined Robin Ventura, John Olerud and Mark Teixeira as just the fourth underclassman to be named Baseball America’s National Player of the Year.
On April 30, 2017, Anthony went 6-for-6 with three home runs and a franchise record 10 RBI in the Nationals’ 23-5 win over the New York Mets. He became the first MLB player with at least 10 RBI in a game since the Angels’ Garret Anderson in 2007 and only one other player in MLB history has driven in at least 10 runs in a so-called “perfect day at the plate” – every at-bat resulting in a hit. He joined Jim Bottomley of the St. Louis Cardinals (in 1924). He also emerged as a top run producer after the ’16 All-Star break, ranking fifth in the NL in RBI over that stretch with 52. In the field, he led all NL third baseman with a .976 fielding percentage in ’16. Anthony burst onto the scene with a superb 2014 season in which he took home the National League Silver Slugger Award for third baseman. He played in just 79 Minor League games before being promoted in 2013 and made his big-league debut on April 21, 2013 vs. the New York Mets at Citi Field.
On June 29, 2010, Anthony was honored by Houston Mayor Annise Parker and the City Council with “Anthony Rendon Day” in Houston.